This guidance document provides a comprehensive defensible framework for establishing and using soil background in risk assessments.

This guidance provides practitioners with recommendations for planning, collecting, processing, and interpreting incremental samples to obtain more representative and reproducible data.

Clarification of information in Incremental Sampling Methodology (ISM-1, 2012) that is outdated, inconsistent, or potentially misleading. Please review this statement before reading the ISM-1 document.

Practical recommendations for planning, designing, implementing, and evaluating in situ remediation projects.

Evaluates the performance of incremental sampling methodology, explains sampling design and laboratory considerations, and discusses its applicability to different contaminants and site conditions.

Helps regulators and other practitioners select the appropriate advanced site characterization tools to support their conceptual site model and remedial planning.

An overview of how to characterize, remediate, and monitor contaminated fractured rock sites, including developing conceptual site models, selecting tools, designing monitoring programs, and evaluating remediation strategies.

Explains how to incorporate bioavailability of contaminants in soil into human health risk assessments by reviewing key concepts, methods, and tools for developing site-specific bioavailability values to improve exposure estimates.

Updates the five previous ITRC MIS documents.